Creatine pills tested for menopause brain fog and fatigue
NCT ID NCT06660004
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested whether taking creatine supplements for 8 weeks could improve fatigue, thinking skills, and brain chemistry in perimenopausal and menopausal women. 36 women took either creatine HCl, creatine ethyl ester, or a placebo. Researchers measured fatigue levels, exercise endurance, brain creatine levels, and cognitive interference. The trial is complete, but results are not yet reported.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
creatine (creatine HCl and creatine ethyl ester)
What this could lead to
If it works, this could point toward a simple dietary supplement to help with fatigue and brain fog during menopause.
What could go wrong
This is a small, early-stage trial with only 36 participants. Results may not apply to all women, and supplements can cause digestive upset or other mild side effects.
Disclaimer
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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FSPE Applied BIoenergetcis Lab
Novi Sad, Vojvodina, 21000, Serbia