Could extended CPAP save preterm Babies' lungs?
NCT ID NCT07417111
First seen Jun 27, 2026 · Last updated Jul 15, 2026 · Updated 2 times
Summary
This study tests whether keeping very preterm babies on CPAP (a breathing machine) until 34 weeks after conception, instead of switching to a nasal cannula, reduces their risk of bronchopulmonary dysplasia (a chronic lung disease) or death. About 860 infants born before 29 weeks will be enrolled. The goal is to see if longer CPAP support leads to better lung outcomes.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- CPAP (continuous positive airway pressure) device
- What this could lead to
- If it works, this could show that keeping very preterm babies on CPAP longer helps prevent a serious lung disease called bronchopulmonary dysplasia.
- What could go wrong
- This is a large trial but still early in testing. The results may not apply to all preterm infants, and CPAP can cause discomfort or nasal injury.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Case Western Reserve University, Rainbow Babies and Children's Hospital
RECRUITINGCleveland, Ohio, 44106, United States
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Cincinnati Children's Medical Center
RECRUITINGCincinnati, Ohio, 45267, United States
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Duke University
RECRUITINGDurham, North Carolina, 27710, United States
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Emory University
RECRUITINGAtlanta, Georgia, 30303, United States
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Northwestern Lurie Children's Hospital of Chicago
RECRUITINGChicago, Illinois, 60611, United States
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Sharp Mary Birch Hospital for Women & Newborns
RECRUITINGSan Diego, California, 92123, United States
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Stanford University
RECRUITINGPalo Alto, California, 94304, United States
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University of Alabama at Birmingham
RECRUITINGBirmingham, Alabama, 35233, United States
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University of Iowa
RECRUITINGIowa City, Iowa, 52242, United States
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University of Mississippi Medical Center - Children's of Mississippi
RECRUITINGJackson, Mississippi, 39216, United States
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University of New Mexico
RECRUITINGAlbuquerque, New Mexico, 87131, United States
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University of Pennsylvania
RECRUITINGPhiladelphia, Pennsylvania, 19104, United States
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University of Texas Health Science Center at Houston
RECRUITINGHouston, Texas, 77030, United States
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University of Texas Southwestern Medical Center at Dallas
RECRUITINGDallas, Texas, 75235, United States
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University of Utah
RECRUITINGSalt Lake City, Utah, 84108, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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