Could a gentler nasal tube replace the CPAP mask for kids with sleep apnea?

NCT ID NCT07600333

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether a high-flow nasal cannula (HFNC) — a soft tube that delivers warm, humidified air through the nose — works as well as the standard CPAP mask for children with moderate-to-severe obstructive sleep apnea. About 258 children aged 2 to 18 will use one of the two devices nightly for 3 months. Researchers will measure how often each device is used, how it affects sleep symptoms and quality of life, and how comfortable it feels. The goal is to find a treatment that kids can tolerate better without losing effectiveness.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

High-Flow Nasal Cannula (HFNC) and Continuous Positive Airway Pressure (CPAP) devices

What this could lead to

If HFNC works as well as CPAP but is more comfortable, it could give children with sleep apnea a better-tolerated treatment option, improving their sleep and quality of life.

What could go wrong

This is an early-stage comparison study, not yet recruiting. HFNC may not be as effective as CPAP, and children might still struggle with adherence. Results may not apply to all ages or severities.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

obstructive sleep apnea syndrome sleep apnea syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • The Hospital for Sick Children

    Toronto, Ontario, Canada

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact