Does the pfizer vaccine work as well in immunosuppressed people? new study aims to find out
NCT ID NCT04780659
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study looked at how well the Pfizer mRNA vaccine triggers an immune response in people with weakened immune systems compared to healthy individuals. About 539 adults received two doses of the vaccine, and researchers measured antibody levels and side effects. The goal was to see if the vaccine protects immunosuppressed people as effectively as it does others.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Pfizer mRNA vaccine (Comirnaty)
What this could lead to
If successful, this could show that the vaccine works well in people with weakened immune systems, helping protect them from COVID-19.
What could go wrong
This is a completed Phase 4 study, so results are already known. However, immune responses may still be weaker in some immunosuppressed groups, and the study does not test long-term protection.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Karolinska University Hospital
Stockholm, Huddinge, 14186, Sweden