Can couples counseling help pregnant women with HIV stay healthy and beat depression?
NCT ID NCT06659315
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests a couple-based problem-solving therapy for pregnant women living with HIV who also have depression. The goal is to improve their mental health and help them stick to their HIV medication, which prevents passing the virus to their baby. The trial will enroll 180 couples in Malawi to see if the approach is feasible and acceptable.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Couples Problem Solving Therapy (behavioral intervention)
- What this could lead to
- If successful, this could provide a practical, scalable way to improve both mental health and HIV medication adherence in pregnant women, reducing mother-to-child transmission of HIV.
- What could go wrong
- This is a small, early-stage feasibility study (180 couples) in one region of Malawi, so results may not apply broadly. The intervention is behavioral and depends on partner participation, which may be challenging.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Invest in Knowledge (IKI)
RECRUITINGZomba, Malawi
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