Can a steroid shot before surgery tame leg swelling?

NCT ID NCT03915223

Completed Symptom relief Sponsor: University Hospital, Clermont-Ferrand Source: ClinicalTrials.gov ↗

First seen Aug 06, 2026 · Last updated Aug 07, 2026 · Updated 1 time

Summary

This trial tests whether giving a steroid injection just before surgery for a broken leg can reduce swelling and pain compared to a placebo. Adults with certain leg fractures who need surgery within 72 hours are randomly assigned to receive either the steroid or a saline injection. The main goal is to see if the steroid helps decrease leg swelling after the operation.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Solumedrol (a steroidal anti-inflammatory drug) injected before surgery
What this could lead to: If effective, this could offer a simple way to reduce swelling and pain after leg fracture surgery, potentially speeding recovery.
What could go wrong: The trial is relatively small and early, and the benefits may not be clear or could come with risks like infection or delayed healing.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

bone fracture Edema Leg Injuries

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

EDEMA FRACTURE LEG INJURIES

Contacts and locations

Locations

CHU de Clermont-Ferrand

Clermont-Ferrand, 63000, France

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