FRACTURE
Clinical trials for FRACTURE explained in plain language.
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Pill power: could oral antibiotics replace IV drips for infected fractures?
Disease control Recruiting nowThis study compares oral (pill) antibiotics to intravenous (IV) antibiotics for treating infected broken bones that haven't healed properly. About 250 adults with this condition will be randomly assigned to receive either oral or IV antibiotics for up to 6 weeks after surgery. Th…
Matched conditions: FRACTURE
Phase: PHASE3 • Sponsor: Major Extremity Trauma Research Consortium • Aim: Disease control
Last updated Jun 27, 2026 13:08 UTC
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Rural program aims to boost osteoporosis drug adherence
Disease control Recruiting nowThis study is testing a fracture liaison service (FLS) combined with medication management for people with osteoporosis in a rural area. The program provides education, monitoring, and follow-up to help patients take their medications as prescribed. Researchers will enroll 200 ad…
Matched conditions: FRACTURE
Sponsor: National Taiwan University Hospital • Aim: Disease control
Last updated Jun 27, 2026 08:06 UTC
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New shoulder implant under study: will it stand the test of time?
Disease control Recruiting nowThis study is checking how long the Medacta Shoulder System lasts and how well it works in 200 people with shoulder issues like arthritis, fractures, or failed previous shoulder replacements. Participants will be followed over time to measure shoulder function, pain, and movement…
Matched conditions: FRACTURE
Sponsor: Medacta International SA • Aim: Disease control
Last updated Jun 27, 2026 07:52 UTC
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Could buprenorphine replace opioids for elderly fracture patients?
Symptom relief Recruiting nowThis study compares buprenorphine to a standard opioid (hydromorphone) for pain relief in adults aged 65 and older who come to the emergency department with a broken bone. Researchers want to see if buprenorphine works just as well but causes fewer side effects like nausea, confu…
Matched conditions: FRACTURE
Phase: PHASE1, PHASE2 • Sponsor: The Cooper Health System • Aim: Symptom relief
Last updated Jul 01, 2026 00:00 UTC
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One shot vs. catheter: which controls pain better after leg fracture surgery?
Symptom relief Recruiting nowThis study tests whether a single injection of a long-acting anesthetic (Exparel) can control pain as well as a catheter that delivers continuous anesthetic after leg fracture surgery. Ninety adults with closed leg fractures will receive either the single shot or the catheter bef…
Matched conditions: FRACTURE
Phase: PHASE4 • Sponsor: George Washington University • Aim: Symptom relief
Last updated Jun 27, 2026 07:55 UTC
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Shower sooner? new study tests best time to bathe after bone surgery
Knowledge-focused Recruiting nowThis study looks at whether it's safe and satisfying to shower early after orthopedic fracture surgery, compared to waiting longer. About 56 adults with arm or leg fractures will be randomly assigned to bathe early or follow the traditional delayed approach. The goal is to see wh…
Matched conditions: FRACTURE
Phase: NA • Sponsor: Hospital for Special Surgery, New York • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:02 UTC
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Massive shoulder replacement study tracks 20,000 patients for over a decade
Knowledge-focused Recruiting nowThis study is tracking 20,000 people who have had or will have shoulder replacement surgery to see how well the implants work over at least 10 years. Researchers will measure pain, daily function, and strength using standard shoulder scores. The goal is to better understand the l…
Matched conditions: FRACTURE
Sponsor: Exactech • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:04 UTC
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Massive study tracks 4,000 Kids' implants for safety
Knowledge-focused Recruiting nowThis study follows 4,000 children who receive orthopedic implants (like rods or screws) during standard care for bone fractures, deformities, or hip problems. Researchers will track how long the implants last, any complications, and how well they work over time. The goal is to ga…
Matched conditions: FRACTURE
Sponsor: University of British Columbia • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:59 UTC