Blood test may spot hidden cancer DNA after surgery
NCT ID NCT05210283
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study is testing a blood test that looks for tiny bits of cancer DNA in the blood after colorectal cancer surgery. The goal is to see if this test can predict whether the cancer will return. Over 1,000 people with stage II or III colorectal cancer will be followed for up to 7 years. The test is not a treatment, but a way to monitor for recurrence.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
ctDNA MRD test (blood test)
What this could lead to
If successful, this blood test could help doctors identify which patients are at risk of cancer returning after surgery, allowing for earlier treatment.
What could go wrong
This is a validation study, not a treatment trial. The test may not be accurate enough to change outcomes, and results may not apply to all patients.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Atrium Health Levine Cancer Institute
Charlotte, North Carolina, 28204, United States
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Atrium Health Wake Forest Baptist Medical Center
Winston-Salem, North Carolina, 27157, United States
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Ballad Health Cancer Center
Kingsport, Tennessee, 37660, United States
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Columbus NCORP
Columbus, Ohio, 43215, United States
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Cross Cancer Institute
Edmonton, Alberta, T6G1Z2, Canada
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Edward Cancer Center
Elmhurst, Illinois, 60126, United States
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Facey Medical Group - Mission Hills - Endoscopy Center & Gastroenterology
Mission Hills, California, 91345, United States
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FirstHealth Outpatient Cancer Center
Pinehurst, North Carolina, 28374, United States
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Illinois Cancer Care
Peoria, Illinois, 61615, United States
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Interstate Medical Office Central
Portland, Oregon, 97227, United States
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Jewish General Hospital
Montreal, Quebec, H3T1E2, Canada
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Lankenau Medical Center
Wynnewood, Pennsylvania, 19096, United States
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Marshfield Medical Center Weston
Weston, Wisconsin, 54476, United States
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McGill University Health - Glen Site
Montreal, Quebec, H4A3J1, Canada
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MedStar Georgetown Cancer Institute at MedStar Georgetown University Hospital
Baltimore, Maryland, 21237, United States
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Mercy Medical Center
Cedar Rapids, Iowa, 52403, United States
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Meritus Center for Clinical Research
Hagerstown, Maryland, 21742, United States
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Metro Minnesota Community Oncology Consortium (MMCORC)
Saint Louis Park, Minnesota, 55426, United States
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Mid Florida Cancer Centers
Orange City, Florida, 32763, United States
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Missouri Baptist Medical Center
St Louis, Missouri, 63131, United States
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Mount Sinai Medical - Comprehensive Cancer Center
Miami Beach, Florida, 33140, United States
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Primsa Health Cancer Institute
Greenville, South Carolina, 29605, United States
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Princess Margaret Cancer Center
Toronto, Ontario, M5G2C1, Canada
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Reading Hospital Hematology Oncology
West Reading, Pennsylvania, 19611, United States
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Sanford Cancer Center
Sioux Falls, South Dakota, 57104, United States
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Sanford Roger Maris Cancer Center
Fargo, North Dakota, 58104, United States
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Torrance Memorial Hunt Cancer Institute
Torrance, California, 90505, United States
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UPMC Hillman Cancer Center
Pittsburgh, Pennsylvania, 15232, United States
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University of Florida Division of Hematology & Oncology
Gainesville, Florida, 32610, United States
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University of Kansas Cancer Center
Westwood, Kansas, 66205, United States
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University of Maryland St. Joseph Medical Center
Towson, Maryland, 21093, United States
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WellSpan York Cancer Center
York, Pennsylvania, 17403, United States