Real-World COPD study tracks benefits of switching to triple inhaler

NCT ID NCT05915182

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study followed 212 adults with moderate to severe COPD in Greece who were prescribed a triple-combination inhaler (Trixeo Aerosphere). Researchers tracked why patients switched from dual therapy and how their symptoms and quality of life changed over 52 weeks. The goal was to see if the switch helps in everyday medical practice, not just in controlled trials.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Budesonide, Glycopyrronium bromide, Formoterol fumarate (Trixeo Aerosphere inhaler)

What this could lead to

If successful, this study could show that switching to triple therapy improves daily life for COPD patients in real-world settings, helping doctors make better treatment decisions.

What could go wrong

This is an observational study, not a controlled trial, so results may be influenced by other factors. It is also small (212 people) and limited to Greece, so findings may not apply everywhere.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

chronic obstructive pulmonary disease COPD, severe early onset lung disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Research Site

    Alexandroupoli, 68100, Greece

  • Research Site

    Athens, 11521, Greece

  • Research Site

    Athens, 11527, Greece

  • Research Site

    Athens, 12462, Greece

  • Research Site

    Athens, 17562, Greece

  • Research Site

    Corfu, 49100, Greece

  • Research Site

    Crete, 71409, Greece

  • Research Site

    Crete, 71500, Greece

  • Research Site

    Crete, 73300, Greece

  • Research Site

    Ioannina, 45500, Greece

  • Research Site

    Larissa, 41110, Greece

  • Research Site

    Pátrai, 26332, Greece

  • Research Site

    Pátrai, 26504, Greece

  • Research Site

    Thessaloniki, 56429, Greece

  • Research Site

    Thessaloniki, 57010, Greece