COPD study seeks to personalize steroid treatment using blood markers

NCT ID NCT06334575

Recruiting now Knowledge-focused Sponsor: Maria Joyera Rodríguez Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study aims to understand why some COPD patients benefit from inhaled corticosteroids (ICS) while others do not, by looking at molecular changes in the body. Researchers will enroll 135 former smokers with stable COPD who are already on dual bronchodilators. Participants will be grouped by their blood eosinophil levels and randomly assigned to receive ICS or continue usual care, with samples taken to identify molecular signatures.

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Conditions

The condition(s) this trial relates to.

chronic obstructive pulmonary disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CHRONIC OBSTRUCTIVE PULMONARY DISEASE

Contacts and locations

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Study contacts

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Locations

Academisch Ziekenhuis Groningen
RECRUITING

Groningen, Netherlands

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Clínic Barcelona
RECRUITING

Barcelona, 08036, Spain

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Imperial College London
NOT_YET_RECRUITING

London, United Kingdom

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Philips University of Marburg
RECRUITING

Marburg, Germany

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Son Espases
RECRUITING

Palma de Mallorca, 07120, Spain

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University of Leicester
NOT_YET_RECRUITING

Leicester, United Kingdom

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