Could a simple ultrasound replace risky scans for kids with Crohn's?
NCT ID NCT03492944
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study compares contrast-enhanced ultrasound to standard CT and MRI scans for detecting bowel inflammation in children aged 10–18 with Crohn's disease. Participants receive an ultrasound with a microbubble contrast agent alongside their regularly scheduled CT or MRI. The goal is to see if the ultrasound can accurately identify and measure inflammation, potentially offering a safer, radiation-free alternative for monitoring disease activity.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Ultrasound Microbubble Contrast Agent (Lumason)
What this could lead to
If ultrasound works as well as CT or MRI, children with Crohn's could avoid radiation and sedation during routine scans.
What could go wrong
This is a small early study (25 children) comparing imaging methods, not testing a treatment. Ultrasound may not be as accurate as standard scans.
Disclaimer
Read more
Show less
This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for CROHN DISEASE are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Show contact details
Enter your email to view the contact information for this study.
By submitting, you agree to our Terms of use
Locations
-
Cincinnati Children's Hospital Medical Center
Cincinnati, Ohio, 45229, United States