Double-Dye MRI could sharpen liver cancer detection

NCT ID NCT02156739

First seen Jan 05, 2026 · Last updated Jun 19, 2026 · Updated 29 times

Summary

This study tests whether using two contrast dyes during MRI can better tell apart benign and malignant liver lesions. About 100 patients with known or suspected liver growths will receive both gadoxetate disodium and gadobutrol before imaging. The goal is to see if the combination improves accuracy compared to using one dye alone.

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Contacts and locations

Locations

  • M D Anderson Cancer Center

    Houston, Texas, 77030, United States

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Gadoxetate disodium and gadobutrol (contrast dyes given by IV)

What this could lead to

If successful, this could lead to more accurate MRI scans for liver lesions, helping doctors tell harmless from cancerous growths without invasive biopsies.

What could go wrong

This is a small, early-stage imaging study, not a treatment trial. The results may not apply to all patients or scanners, and the contrast dyes carry a small risk of allergic reaction or kidney injury.

Conditions

The condition(s) this trial relates to.

Digestive System Diseases hepatocellular carcinoma liver cancer liver disorder metastatic malignant neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.