Which progesterone form is best for IVF? new study aims to find out

NCT ID NCT07461909

Recruiting now Knowledge-focused Sponsor: Instituto Valenciano de Infertilidade de Lisboa Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study compares two common forms of vaginal progesterone—soft capsules and pessaries—used during frozen embryo transfer. Researchers want to see which one women find more satisfying, convenient, and tolerable. About 400 women will use one of the two forms and report their experiences through online surveys. The study also checks hormone levels and pregnancy outcomes, but its main goal is to understand patient preferences.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: vaginal progesterone
What this could lead to: If successful, this could help doctors and patients choose the more convenient and tolerable progesterone formulation for frozen embryo transfer, potentially improving the experience.
What could go wrong: This is an observational study, not a randomized trial, so results may be influenced by patient or doctor preferences. It does not test a new treatment, only compares existing options.

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Conditions

The condition(s) this trial relates to.

infertility disorder Patient Satisfaction

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ARTIFICIAL CYCLE FROZEN EMBRYO TRANSFER (FET) INFERTILITY NATURAL CYCLE

Contacts and locations

Locations

Instituto Valenciano de Infertilidade (IVI Lisboa)
RECRUITING

Lisbon, 1800-282, Portugal

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