Which steroid works best for COPD attacks? major trial aims to find out

NCT ID NCT06892210

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study compares two steroids, hydrocortisone and prednisolone, in 2000 adults over 40 with COPD flare-ups. The goal is to see which one reduces hospital readmissions and deaths within 30 days. Participants are randomly assigned to one of the two treatments.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

hydrocortisone and prednisolone (corticosteroids)

What this could lead to

If it works, this could identify which steroid works best for COPD flare-ups, potentially reducing hospital readmissions and deaths.

What could go wrong

This is a late-stage trial but compares two similar drugs already in use, so a dramatic breakthrough is unlikely. Results may show no meaningful difference.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for CHRONIC OBSTRUCTIVE PULMONARY DISEASE (COPD) are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

chronic obstructive pulmonary disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Amager Hospital

    RECRUITING

    Copenhagen, Copenhagen City, 2300, Denmark

  • Bispebjerg Hospital

    RECRUITING

    Copenhagen, Copenhagen City, 2400, Denmark

  • Bornholm Hospital

    RECRUITING

    Rønne, Bornholm, 3700, Denmark

  • Frederiksberg Hospital

    RECRUITING

    Frederiksberg, Copenhagen City, 2000, Denmark

  • Gentofte Hospital

    RECRUITING

    Hellerup, Copenhagen City, 2900, Denmark

  • Herlev Hospital

    RECRUITING

    Herlev, Copnhagen Surroundings, 2730, Denmark

  • Holbæk Sygehus

    RECRUITING

    Holbæk, Region Sjælland, 4300, Denmark

  • Hvidovre Hospital

    RECRUITING

    Hvidovre, Copnhagen Surroundings, 2650, Denmark

  • Nordsjællands Hospital

    RECRUITING

    Hillerød, North Zealand, 3400, Denmark

  • Næstved Sygehus

    RECRUITING

    Næstved, Region Sjælland, 4700, Denmark

  • Ringsted Sygehus

    RECRUITING

    Ringsted, Region Sjælland, 4100, Denmark

  • Slagelse Sygehus

    RECRUITING

    Slagelse, Region Sjælland, 4200, Denmark

  • University Hospital of Region Zealand, Køge

    RECRUITING

    Køge, Region Sjælland, 4600, Denmark

  • University Hospital of Region Zealand, Roskilde

    RECRUITING

    Roskilde, Region Sjælland, 4000, Denmark