Prolapse surgery showdown: which procedure wins?

NCT ID NCT05063331

Ongoing Disease control Sponsor: University Hospitals Cleveland Medical Center Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study compares two common surgeries for uterine prolapse: a minimally invasive sacrocolpopexy and a vaginal hysterectomy with uterosacral ligament suspension. Researchers will track 300 women to see which surgery has fewer failures and complications from the patient's perspective. The goal is to help women and their doctors choose the best option.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: surgery (minimally invasive sacrocolpopexy or vaginal hysterectomy with uterosacral ligament suspension)
What this could lead to: If this trial succeeds, it could help doctors and patients choose the better surgical option for treating uterine prolapse, leading to fewer failures and complications.
What could go wrong: This is an observational comparison, not a blinded trial, so results may be influenced by patient or surgeon preferences. Both surgeries have risks like pain, infection, or prolapse recurrence.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

pelvic organ prolapse prolapse of female genital organ Uterine Prolapse

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

UTERINE PROLAPSE

Contacts and locations

Locations

Cleveland Clinic

Cleveland, Ohio, 44195, United States
Duke University

Durham, North Carolina, 27707, United States
Mayo Clinic

Jacksonville, Florida, 32224, United States
MetroHealth Medical Center

Cleveland, Ohio, 44109, United States
Northwestern Medicine

Chicago, Illinois, 60611, United States
University Hospitals Cleveland Medical Center

Cleveland, Ohio, 44106, United States
University of Pittsburgh, UPMC Magee-Womens Hospital

Pittsburgh, Pennsylvania, 15213, United States

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