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Ventilator showdown: which pressure setting saves lungs best?

NCT ID NCT06697717

Completed Knowledge-focused Sponsor: XiaoJing Zou,MD Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jul 01, 2026 · Updated 3 times

Summary

This study looks at 20 patients who have both high pressure in their belly (intra-abdominal hypertension) and severe lung injury (ARDS). Researchers will compare two methods for setting the ventilator's positive end-expiratory pressure (PEEP): one based on lung pressure measurements and another using electrical impedance tomography (EIT) imaging. The goal is to see which method better improves lung function and avoids harming other organs. This is a small, early study to gather knowledge, not to test a new treatment.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
ventilator pressure setting methods
What this could lead to
If successful, this could identify a better way to set ventilator pressures for patients with both high abdominal pressure and lung injury, potentially reducing lung damage and improving outcomes.
What could go wrong
This is a very small, early-stage study with only 20 participants, so results may not apply to all patients. It compares two methods but does not test a new drug or device, so direct patient benefits are uncertain.

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Conditions

The condition(s) this trial relates to.

acute respiratory distress syndrome adult acute respiratory distress syndrome Intra-Abdominal Hypertension

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ACUTE RESPIRATORY DISTRESS SYNDROME (ARDS) INTRA-ABDOMINAL HYPERTENSION

Contacts and locations

Locations

  • Wuhan Union Hospital

    Wuhan, Hubei, China

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