Laser vs. ultrasound: which zaps Crow's feet best?

NCT ID NCT01529983

First seen Jul 01, 2026 · Last updated Jul 01, 2026

Summary

This pilot study compares two FDA-approved cosmetic procedures—fractional laser and high-intensity focused ultrasound—for treating wrinkles around the eyes (crow's feet and lower eyelid lines). About 20 adults aged 35–60 with moderate wrinkles will receive one treatment on each side of the face, and doctors will compare results at 1 and 3 months. The goal is to see which method works better and is preferred by patients.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

1550-nm fractional laser and high-intensity focused ultrasound

What this could lead to

If one method proves clearly better, it could become the preferred option for treating crow's feet and lower eyelid wrinkles.

What could go wrong

This is a very small early-phase pilot study with only 20 people, so results may not apply to everyone. Both procedures can cause temporary redness, swelling, or discomfort.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Northwestern University Feinberg School of Medicine, Department of Dermatology

    Chicago, Illinois, 60611, United States