Botox vs. xeomin: which smooths wrinkles better?
NCT ID NCT02019004
First seen Jul 01, 2026 · Last updated Jul 01, 2026
Summary
This study compares two popular wrinkle treatments—Botox and Xeomin—for forehead lines and frown lines between the eyebrows. Twenty healthy adults aged 20 to 65 with moderate wrinkles receive both treatments on different sides of their face, and doctors rate the results over six months. The goal is to see if one works better or lasts longer.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
onabotulinum toxin A (Botox) and incobotulinum toxin A (Xeomin)
What this could lead to
If one works better or lasts longer, it could help people choose the best option for wrinkle treatment.
What could go wrong
This is a very small early-phase study with only 20 people, so results may not apply to everyone. Side effects like bruising or drooping are possible.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Northwestern University Department of Dermatology
Chicago, Illinois, 60611, United States