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Can a Collagen-Boosting injection tighten loose neck skin?

NCT ID NCT07689344

Symptom relief Sponsor: Institute of Dermatology, Thailand Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jul 08, 2026 · Last updated Jul 09, 2026 · Updated 1 time

Summary

This pilot study investigates whether injections of Poly-L-Lactic acid (PLLA), a collagen-stimulating substance, can safely improve skin laxity and wrinkles on the neck. Ten adults aged 30-60 with mild to severe neck skin looseness will receive a single treatment session. Researchers will assess changes using clinical photos and a standardized scale over 24 weeks, along with participant satisfaction.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Poly-L-Lactic Acid (Sculptra) injection
What this could lead to
If effective, PLLA injections could offer a non-surgical option to tighten loose neck skin and reduce wrinkles.
What could go wrong
This is a very small pilot study with only 10 participants, so results may not apply broadly. The treatment may not work or could cause side effects like swelling or bruising.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 10 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Jul 2026

An estimate. Start dates often move.

Expected to finish

Sep 2026

An estimate. End dates often move.

Lead sponsor

A government agency

The lead sponsor is a government body.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

30 to 60 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Thai male or female participants aged 30-60 years * Individuals who wish to improve neck skin laxity * Presence of neck skin laxity grade 1-4 according to the Neck Skin Laxity Scale (NSL scale) Exclusion Criteria: * Pregnant or breastfeeding women * History of allergy or hypersensitivity to local anesthetics or components of collagen-stimulating substances * Active autoimmune disease requiring systemic treatment * History of cosmetic procedures in the neck area, including laser treatment, radiofrequency, or ultrasound-based devices within 6 months prior to treatment * History of dermal filler injection in the neck area * History of botulinum toxin injection in the neck area within 6 months prior to treatment

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Conditions

The condition(s) this trial relates to.

cutis laxa

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Skin aging Wrinkles

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Institute of Dermatology

    Ratchathewi, Bangkok, 10400, Thailand

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