5-Day brain zapping trial aims to lift severe depression
NCT ID NCT06895863
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This trial tests a new, accelerated form of brain stimulation for people with severe depression that hasn't improved with medication. Over five days, 78 participants will receive 25 sessions of magnetic stimulation, either targeting a standard brain area or a new one, or a sham (fake) treatment. The goal is to see if this fast, personalized approach can safely and quickly ease depression symptoms.
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Centre of Neuropsychiatric Depression Research
RECRUITINGGlostrup Municipality, 2600, Denmark
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Danish Research Centre for Magnetic Resonance
NOT_YET_RECRUITINGHvidovre, 2650, Denmark
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Mental Health Center North Zealand
NOT_YET_RECRUITINGHilleroed, 3400, Denmark
Contact Phone: •••-•••-•••• Email: •••••@•••••
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
transcranial magnetic stimulation (TMS) using intermittent theta burst stimulation (iTBS)
What this could lead to
If it works, this could offer a fast, non-invasive treatment option for people with severe depression that hasn't responded to medication.
What could go wrong
This is a relatively small, early-stage trial testing two different brain targets. It's not yet proven to work, and the effects may be modest or not last long.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.