Heart valve study: could random placement be just as good?

NCT ID NCT05779787

Recruiting now Knowledge-focused Sponsor: Niguarda Hospital Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looks at people getting a new heart valve (TAVR) for a narrowed aortic valve. It compares two ways of placing the valve: one carefully aligned and one random. The goal is to see if the random method still allows doctors to easily reach the heart arteries later if needed. 100 participants will be followed to measure how well doctors can re-enter the arteries after the procedure.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this could show that a simpler, faster valve placement is just as good for allowing future heart procedures, potentially simplifying TAVR for many patients.
What could go wrong: This is a small, early-stage study (100 patients) looking at technical success, not long-term health outcomes. The results may not apply to all patients or valve types.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

aortic valve stenosis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

AORTIC VALVE STENOSIS TRANSCATHETER AORTIC VALVE REPLACEMENT

Contacts and locations

Locations

ASST GOM Niguarda
RECRUITING

Milan, Lombardy, 20162, Italy

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