New IV pain relief combo for children enters final testing phase

NCT ID NCT07225634

Not yet recruiting Symptom relief Sponsor: AFT Pharmaceuticals, Ltd. Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jul 02, 2026 · Updated 2 times

Summary

This study tests a new intravenous medicine called Combogesic IV, which combines two common pain relievers (acetaminophen and ibuprofen) into one infusion. It will involve 60 children aged 2 to 17 with acute pain who need IV pain relief. The goal is to see how the body processes the drug and to check its safety, with the hope of providing a non-opioid option for managing pain in kids.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Combogesic IV (a combination of acetaminophen and ibuprofen given through a vein)
What this could lead to: If successful, this could provide a safe, effective option for managing acute pain in children without relying on opioids.
What could go wrong: This is a small, early-stage trial focused on safety and drug processing, not on proving pain relief. The results may not apply to all children or pain types.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Acute Pain

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ACUTE PAIN

Contacts and locations

Locations

Nemours Children's Health

Orlando, Florida, 32827, United States

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