Double scan strategy could sharpen prostate cancer staging

NCT ID NCT07455097

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looks at whether combining PSMA-PET/CT and MRI scans can more accurately determine the extent of prostate cancer in men with intermediate- or high-risk disease. Researchers will compare scan results with tissue samples from 600 men who had their prostate removed. The goal is to improve staging and guide personalized treatment decisions.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
PSMA-11 (diagnostic tracer)
What this could lead to
If successful, this could lead to more accurate staging of prostate cancer, helping doctors choose better treatments and avoid unnecessary surgery.
What could go wrong
This is a retrospective analysis, not a controlled trial, so results may not apply to all patients. The imaging techniques are already in use, so the benefit may be modest.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Fortis Hospital

    Kolkata, India

  • KU Leuven

    Leuven, Belgium

  • Ludwig-Maximilians-University Munich

    Munich, Germany

  • Lund University Hospital

    Lund, Sweden

  • Marienhospital Herne

    Herne, Germany

  • Medical University Vienna

    Vienna, Austria

  • San Raffaele University Hospital Milan

    Milan, Italy

  • University Hospital Bern

    Bern, Switzerland

  • University Hospital Düsseldorf

    Düsseldorf, 40225, Germany

  • University Hospital Tübingen

    Tübingen, Germany

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