New drug cocktail aims to shrink Hard-to-Treat kidney tumors

NCT ID NCT04981509

First seen Nov 01, 2025 · Last updated May 13, 2026 · Updated 28 times

Summary

This study tests whether a combination of three drugs—bevacizumab, erlotinib, and atezolizumab—can shrink or stabilize advanced kidney cancer in people with a rare inherited form (HLRCC) or sporadic papillary kidney cancer. The drugs work by cutting off the tumor's blood supply, blocking cancer growth signals, and boosting the immune system. About 65 adults with advanced disease that has spread will receive the treatment to see if it is safe and effective.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Emory Saint Joseph's Hospital

    RECRUITING

    Atlanta, Georgia, 30342, United States

    Contact

    Contact Phone: •••-•••-••••

  • Emory University Hospital Midtown

    RECRUITING

    Atlanta, Georgia, 30308, United States

    Contact

    Contact Phone: •••-•••-••••

  • Emory University Hospital/Winship Cancer Institute

    RECRUITING

    Atlanta, Georgia, 30322, United States

    Contact

    Contact Phone: •••-•••-••••

  • Laura and Isaac Perlmutter Cancer Center at NYU Langone

    ACTIVE_NOT_RECRUITING

    New York, New York, 10016, United States

  • M D Anderson Cancer Center

    RECRUITING

    Houston, Texas, 77030, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • NCI - Center for Cancer Research

    RECRUITING

    Bethesda, Maryland, 20892, United States

    Contact

    Contact Phone: •••-•••-••••

  • NYU Langone Hospital - Long Island

    ACTIVE_NOT_RECRUITING

    Mineola, New York, 11501, United States

  • National Institutes of Health Clinical Center

    SUSPENDED

    Bethesda, Maryland, 20892, United States

  • Northwestern University

    RECRUITING

    Chicago, Illinois, 60611, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Ohio State University Comprehensive Cancer Center

    RECRUITING

    Columbus, Ohio, 43210, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Rutgers Cancer Institute of New Jersey

    RECRUITING

    New Brunswick, New Jersey, 08903, United States

    Contact

    Contact Phone: •••-•••-••••

  • UC San Diego Moores Cancer Center

    RECRUITING

    La Jolla, California, 92093, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • University of Pittsburgh Cancer Institute (UPCI)

    RECRUITING

    Pittsburgh, Pennsylvania, 15232, United States

    Contact

    Contact Phone: •••-•••-••••

Conditions

Explore the condition pages connected to this study.