New drug duo takes on tough cancers: hope for advanced bladder, kidney, and melanoma patients

NCT ID NCT05661955

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This study is testing a new combination of two immunotherapy drugs (BGB-A445 and tislelizumab) in about 113 people with advanced bladder, kidney, or skin cancer that has spread. The goal is to see if the combo can shrink tumors and how safe it is. Participants must have already tried at least one prior treatment.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary โ€” we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

melanoma non-cutaneous melanoma renal cell carcinoma transitional cell carcinoma urothelial carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Beijing Cancer Hospital

    Beijing, Beijing Municipality, 100142, China

  • Fujian Cancer Hospital

    Fuzhou, Fujian, 350014, China

  • Guangxi Medical University Cancer Hospital

    Nanning, Guangxi, 530021, China

  • Jining No1 Peoples Hospital West Branch

    Jining, Shandong, 272000, China

  • Liaoning Cancer Hospital and Institute

    Shenyang, Liaoning, 110042, China

  • Nanjing Drum Tower Hospital,the Affiliated Hospital of Nanjing University Medical School

    Nanjing, Jiangsu, 210008, China

  • Shandong Cancer Hospital

    Jinan, Shandong, 250117, China

  • Shanxi Provincial Cancer Hospital

    Taiyuan, Shanxi, 030013, China

  • Sun Yat Sen University Cancer Center

    Guangzhou, Guangdong, 510060, China

  • The First Affiliated Hospital of Wenzhou Medical University

    Wenzhou, Zhejiang, 325000, China

  • The First Affiliated Hospital of Zhengzhou University

    Zhengzhou, Henan, 450052, China

  • The First Hospital of Jilin University

    Changchun, Jilin, 130021, China

  • The Second Hospital and Clinical Medical School, Lanzhou University

    Lanzhou, Gansu, 730030, China

  • The Second Xiangya Hospital of Central South University

    Changsha, Hunan, 410011, China

  • Tianjin Medical University Cancer Institute and Hospital

    Tianjin, Tianjin Municipality, 300060, China

  • Tongji Hospital of Tongji Medical College Huazhong University of Science and Technology

    Wuhan, Hubei, 430030, China

  • West China Hospital, Sichuan University

    Chengdu, Sichuan, 610041, China

  • Zhujiang Hospital of Southern Medical University

    Guangzhou, Guangdong, 510000, China