Can a simple blood test replace colonoscopy for cancer screening?
NCT ID NCT07090291
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study compares three ways to screen for colorectal cancer in average-risk people aged 45-74: colonoscopy, a stool test (FIT), and a stool test plus a blood test. Over 60,000 participants will be randomly assigned to one of the three methods. The goal is to see if the simpler tests are as good as colonoscopy at reducing deaths from colorectal cancer over 10 years.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
What this could lead to
If successful, this could show that simpler, non-invasive tests like FIT or a blood test are as effective as colonoscopy for screening, potentially making screening easier and more accessible.
What could go wrong
This is a large trial but results won't be available for 10 years. The blood test is still experimental, and it may not prove as accurate or effective as hoped.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Maoming People's Hospital
RECRUITINGGuangdong, China
Contact
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Nanjing Medical University
RECRUITINGNanjing, China
Contact Email: •••••@•••••
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Shanghai Municipal Center For Disease Control & Prevention
RECRUITINGShanghai, China
Contact
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Sichuan Cancer Hospital & Institute, Sichuan Cancer Center
RECRUITINGSichuan, China
Contact
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Sun Yat-sen University Cancer Center
RECRUITINGGuandong, China
Contact
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The Fourth Hospital of Hebei Medical University
RECRUITINGHebei, China
Contact Email: •••••@•••••
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Zhejiang Provincial Center for Disease Control and Prevention
RECRUITINGZhejiang, China
Contact