New collagen patch shows promise for stubborn leg ulcers
NCT ID NCT06831760
First seen Jun 24, 2026 · Last updated Jun 26, 2026 · Updated 1 time
Summary
This study tested two types of skin substitutes for treating venous leg ulcers, which are slow-healing sores caused by poor blood flow in the legs. Sixty adults with these ulcers received either a collagen-based skin substitute or a dehydrated human amnion/chorion membrane, both applied weekly with standard wound care. The goal was to see which one helped wounds heal faster and improve tissue health, measured by wound size and microscopic changes in biopsied tissue.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Type-I Collagen-based Skin Substitute and Dehydrated Human Amnion/Chorion Membrane
- What this could lead to
- If successful, this could show that a collagen-based skin substitute heals venous leg ulcers faster or better than the current amnion membrane treatment, offering a new option for patients.
- What could go wrong
- This is a small, completed trial with only 60 participants. The results may not apply to all patients, and the benefits over standard care are not yet proven in larger studies.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for VENOUS LEG ULCERS are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Adichunchanagiri Institute of Medical Sciences
Mandya, Karnataka, 571448, India
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Placental patch could speed healing of stubborn leg wounds
- Cord tissue dressings aim to heal stubborn leg wounds
- New gel could replace scraping for leg ulcer cleaning
- Sound waves instead of surgery: new device tested for vein disease
- Vitamin B5 injections could speed up chronic wound healing
- New tool aims to spot wound healing hurdles early