Can collagen supplements help preserve muscle after Weight-Loss surgery?
NCT ID NCT07809152
First seen Sep 09, 2026 · Last updated Sep 10, 2026 · Updated 1 time
Summary
Researchers at Mudanya University are observing adults who have had sleeve gastrectomy to see whether taking collagen-containing supplements relates to differences in muscle mass, body composition, and body image. Participants choose on their own whether to use collagen supplements, and the study team provides no supplement or advice. Everyone is followed through routine clinic visits for six months after surgery, with body measurements taken by bioelectrical impedance and body image scored using a validated questionnaire.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- collagen-containing dietary supplements
- What this could lead to
- If a link appears, it could guide future research into whether collagen supplements help preserve muscle after weight-loss surgery.
- What could go wrong
- This observational study cannot prove cause and effect, since participants choose on their own whether to take collagen. Any differences seen might come from other habits, and the small size limits how much the results can be generalised.
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Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 52 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Jul 2026
- Expected to finish
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Feb 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Adult patients aged 18-65 years who underwent sleeve gastrectomy and are under routine postoperative follow-up at the General Surgery outpatient clinic of a private hospital in Bursa, Türkiye. Eligible patients meet current ASMBS/IFSO criteria for metabolic and bariatric surgery (BMI ≥ 35 kg/m², or BMI 30-34.9 kg/m² with an obesity-related metabolic comorbidity). Participants are naturally grouped according to their own preference to use or not use a collagen-containing supplement following surgery.
- Ages
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18 to 65 years
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Patients with a BMI ≥ 35 kg/m², regardless of the presence of comorbidities * Patients with a BMI of 30-34.9 kg/m² who have an obesity-related metabolic disease and are considered eligible for surgical treatment * Patients who have undergone metabolic and bariatric surgery (MBS) in accordance with current ASMBS/IFSO guidelines (Eisenberg et al., 2022) * Patients under regular postoperative follow-up * Age 18-65 years Exclusion Criteria: * Inflammatory bowel disease * History of upper gastrointestinal bleeding * Severe psychiatric disorders * Active cancer diagnosis * Pregnancy or breastfeeding * Alcohol or substance dependence * Physical limitations preventing participation in exercise
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Yıldırım Doruk Hastanesi
RECRUITINGBursa, Yıldırım, Turkey (Türkiye)
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