New combo technique aims to stop colon polyps from coming back

NCT ID NCT06937671

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether adding a hot tool to the standard cold removal of large colon polyps lowers the chance of polyps growing back. About 194 adults with flat or slightly raised polyps at least 20 mm wide will be randomly assigned to one of two procedures. Participants will have a follow-up colonoscopy 3 to 6 months later to check for recurrence and complications.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Endoscopic mucosal resection (EMR) procedure

What this could lead to

If successful, this could establish a safer, more effective standard technique for removing large colon polyps, reducing the need for repeat procedures.

What could go wrong

This is a relatively small, early-stage trial comparing two procedural variations. Results may not apply to all polyp types or settings, and both techniques carry risks like bleeding or perforation.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for COLORECTAL POLYP are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

polyp of colon polyp of large intestine

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Cleveland Clinic

    RECRUITING

    Cleveland, Ohio, 44195, United States

    Contact

    Contact

  • Cleveland Clinic Weston

    RECRUITING

    Weston, Florida, 33331, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact