Could cocoa extract help tame migraines? scientists launch pilot study
NCT ID NCT06808230
First seen Jun 29, 2026 · Last updated Jun 30, 2026 · Updated 1 time
Summary
This pilot study explores whether taking high-dose cocoa extract supplements is feasible and acceptable for people with episodic migraine. Researchers will compare two doses of cocoa extract to a placebo, tracking how many participants stick with the daily pills for 12 weeks. The study also collects data on migraine days and severity, but its main goal is to see if a larger trial is possible.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
cocoa extract (dietary supplement)
What this could lead to
If successful, this could pave the way for larger trials testing cocoa flavanols as a potential dietary approach to reduce migraine frequency.
What could go wrong
This is a small pilot study focused on feasibility, not on proving effectiveness. It may not show any benefit for migraines, and high doses could cause side effects.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Brigham and Women's Hospital
RECRUITINGBoston, Massachusetts, 02115, United States
Contact Email: •••••@•••••