Coaching plus ketamine: a new hope for stubborn depression?

NCT ID NCT07563868

First seen Jun 27, 2026 · Last updated Jul 24, 2026 · Updated 2 times

Summary

This study at Massachusetts General Hospital tests whether adding coaching sessions to standard ketamine or esketamine treatment can help people with treatment-resistant depression. About 20 adults already on maintenance ketamine will receive 12 coaching sessions over 3 months. The goal is to see if coaching is practical, well-liked, and might reduce how often ketamine treatments are needed.

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Conditions

The condition(s) this trial relates to.

Depression Depressive Disorder, Treatment-Resistant

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Massachusetts General Hospital

    RECRUITING

    Boston, Massachusetts, 02114, United States

  • Massachusetts General Hospital's Depression and Clinical Research program

    RECRUITING

    Boston, Massachusetts, 02114, United States

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