New combo aims to control CLL in just one year
NCT ID NCT06333262
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests a one-year treatment plan using two drugs, pirtobrutinib and obinutuzumab, for people with chronic lymphocytic leukemia (CLL) or small lymphocytic lymphoma (SLL) who have not had treatment before. The goal is to see if this fixed-duration therapy can control the disease effectively. About 60 participants will receive the combination over 12 cycles.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Beth Israel Deaconess Medical Center
RECRUITINGBoston, Massachusetts, 02215, United States
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Brigham & Women's Hospital
RECRUITINGBoston, Massachusetts, 02215, United States
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Dana-Farber Cancer Institute
RECRUITINGBoston, Massachusetts, 02215, United States
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New England Cancer Specialists
RECRUITINGScarborough, Maine, 04074, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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- Can a Three-Drug combo outsmart High-Risk CLL?
- Can a gentler dose of zanubrutinib keep CLL at bay in the very elderly?
- Can a Two-Drug combo wipe out hidden leukemia cells?
- Can a Chemo-Free pill combo outsmart leukemia at first diagnosis?