New hope for CLL: Year-Long drug combo aims to control cancer without lifelong treatment

NCT ID NCT06333262

First seen Jan 28, 2026 · Last updated May 16, 2026 · Updated 13 times

Summary

This study tests a one-year treatment plan using two drugs, pirtobrutinib and obinutuzumab, for people with untreated chronic lymphocytic leukemia (CLL) or small lymphocytic lymphoma (SLL). The goal is to see if this fixed-duration therapy can effectively control the disease without needing ongoing medication. About 60 participants will receive the combination over 12 cycles, and researchers will measure how many achieve a complete response.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Beth Israel Deaconess Medical Center

    RECRUITING

    Boston, Massachusetts, 02215, United States

    Contact

    Contact

  • Brigham & Women's Hospital

    RECRUITING

    Boston, Massachusetts, 02215, United States

    Contact

    Contact

  • Dana-Farber Cancer Institute

    RECRUITING

    Boston, Massachusetts, 02215, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • New England Cancer Specialists

    RECRUITING

    Scarborough, Maine, 04074, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

Conditions

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