Could an allergy pill help heal the brain in MS? new trial aims to find out

NCT ID NCT06065670

Not yet recruiting Disease control Sponsor: University of California, San Francisco Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether clemastine fumarate, an over-the-counter allergy medication, can repair damaged nerve insulation (myelin) in people with multiple sclerosis. About 44 adults with relapsing-remitting MS will receive either the drug or a placebo for 3 months, then all will get the drug for 3 more months. Researchers will use special MRI scans to measure myelin repair in the brain.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

demyelinating disease Marchiafava-Bignami disease multiple sclerosis relapsing-remitting multiple sclerosis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CLINICALLY ISOLATED SYNDROME, CNS DEMYELINATING DEMYELINATING DISEASES DEMYELINATION; CORPUS CALLOSUM MULTIPLE SCLEROSIS ACUTE AND PROGRESSIVE MULTIPLE SCLEROSIS BRAIN LESION

Contacts and locations

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Study contacts

Contact

Phone: •••-•••-•••• Email: •••••@•••••

Locations

Sandler Neurosciences Building, Neurological Clinical Research Unit

San Francisco, California, 94107, United States

Contact

Contact Phone: •••-•••-•••• Email: •••••@•••••