HIV heart risk targeted: new drug trial aims to quiet arterial inflammation

NCT ID NCT05488431

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether bempedoic acid, a cholesterol-lowering drug, can reduce artery inflammation and improve heart health in people with HIV. About 121 adults aged 40 and older with well-controlled HIV and at least one heart disease risk factor will receive either the drug or a placebo for 52 weeks. Researchers will use advanced imaging to measure changes in arterial inflammation and plaque buildup.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

atherosclerosis cardiovascular disorder Dyslipidemias HIV infectious disease hyperlipidemia inherited lipid metabolism disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • San Francisco General Hospital

    RECRUITING

    San Francisco, California, 94110, United States

    Contact

    Contact

    Contact

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact

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  • UCLA Center for Clinical AIDS Research and Education (CARE)

    RECRUITING

    Los Angeles, California, 90095, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact

  • UT Health Houston

    RECRUITING

    Houston, Texas, 77030, United States

    Contact Email: •••••@•••••

    Contact