Can a simple air cleaner ease COPD symptoms?

NCT ID NCT06376994

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether placing two high-efficiency air cleaners in the homes of 770 people with COPD can reduce flare-ups and improve quality of life over a year. Participants receive either active cleaners that remove particles and gases, or sham cleaners that look and sound the same but don't filter. The goal is to see if cleaner indoor air helps manage this chronic lung disease.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

HEPA and activated carbon air cleaners

What this could lead to

If it works, this could show that improving indoor air quality reduces COPD symptoms and flare-ups, offering a simple, non-drug way to manage the disease.

What could go wrong

This is a large phase 3 trial, but air cleaners may not significantly affect COPD outcomes if outdoor exposure or other triggers dominate. The sham devices mimic real ones, so blinding is good, but the benefit may be modest.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

chronic obstructive pulmonary disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Beth Israel Deaconess Medical Center

    NOT_YET_RECRUITING

    Boston, Massachusetts, 02215, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Cleveland Clinic

    NOT_YET_RECRUITING

    Cleveland, Ohio, 44195, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Dartmouth Hitchcock

    NOT_YET_RECRUITING

    Lebanon, New Hampshire, 03756, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Johns Hopkins

    RECRUITING

    Baltimore, Maryland, 21224, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Reading Hospital

    RECRUITING

    West Reading, Pennsylvania, 19611, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Tidal Health

    RECRUITING

    Salisbury, Maryland, 21801, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • University of Alabama, Lung Health Center

    RECRUITING

    Birmingham, Alabama, 35233, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • University of California, Los Angeles

    RECRUITING

    Los Angeles, California, 90095, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • University of Iowa

    RECRUITING

    Iowa City, Iowa, 52242, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • University of Maryland

    RECRUITING

    Baltimore, Maryland, 21201, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • University of Michigan

    RECRUITING

    Ann Arbor, Michigan, 48109, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact