New radiation patch implanted during surgery aims to stop sarcoma from coming back

NCT ID NCT04033081

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study is testing a device called CivaSheet, a permanent radiation patch placed inside the body during surgery to kill any remaining sarcoma cells. About 100 people with sarcoma in the abdomen, pelvis, or trunk will be followed for 5 years to see how safe it is and whether it helps prevent the cancer from returning. The main focus is on serious side effects and how well the radiation targets the right area.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

CivaSheet (a permanent radiation implant placed during surgery to target leftover cancer cells)

What this could lead to

If successful, this could provide a new way to reduce sarcoma recurrence after surgery by delivering targeted radiation directly to the tumor bed.

What could go wrong

This is a single-arm registry, not a randomized trial, so it cannot prove the device is better than standard care. Risks include radiation-related side effects and the need for additional surgeries.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

sarcoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Fox Chase Cancer Center

    Philadelphia, Pennsylvania, 19111, United States