Which antibiotic wins for liver infection? new study compares ciprofloxacin and ceftriaxone

NCT ID NCT07552870

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study compared two antibiotics—ciprofloxacin and ceftriaxone—given intravenously to 310 patients with liver cirrhosis who developed a serious infection called spontaneous bacterial peritonitis. The goal was to see which drug better controlled fever, abdominal pain, and infection markers after 48 hours. The trial has completed, and results may help guide treatment choices for this life-threatening condition.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

ciprofloxacin and ceftriaxone (antibiotics given intravenously)

What this could lead to

If one antibiotic proves more effective, it could become the preferred treatment for this serious infection in cirrhosis patients, potentially reducing hospital deaths.

What could go wrong

This is a single-center study with a moderate number of participants. Results may not apply to all patients, and both antibiotics have known side effects like allergic reactions or antibiotic resistance.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

cirrhosis of liver Fibrosis infectious peritonitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Nishtar Hospital

    Multan, Punjab Province, 60000, Pakistan