Antibiotic shots around wounds could speed healing in new trial

NCT ID NCT06327113

Recruiting now Disease control Sponsor: University of California, Los Angeles Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This phase 2 trial tests whether injecting antibiotics directly into the tissue around chronic wounds helps them heal better than standard care alone. About 60 adults with non-healing wounds on their legs, arms, or trunk will either receive the antibiotic injections plus usual wound care, or usual care alone. The study will track side effects and measure wound size and closure over six months.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Cefazolin (an antibiotic) injected into the tissue around the wound
What this could lead to: If it works, this could provide a new way to treat stubborn chronic wounds that don't heal with standard care alone.
What could go wrong: This is a small early-phase trial focused on safety, so it may not prove the treatment works. The antibiotic injections could cause pain, infection, or allergic reactions.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

chronic ulcer of skin

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

NON-HEALING WOUND

Contacts and locations

Locations

University of California, Los Angeles
RECRUITING

Los Angeles, California, 90095, United States

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Other studies related to the condition(s) this trial covers.