Scientists dig into Cholesterol's hidden secrets to fight heart disease
NCT ID NCT04061018
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study looked at 86 people with very high or very low cholesterol efflux—a measure of how well the body removes cholesterol from cells. Researchers analyzed their genes, proteins, and lipids to find clues that could lead to new ways to prevent or reverse heart disease. The goal was to identify new targets for future treatments, not to test a specific drug.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- What this could lead to
- If successful, this research could point toward new targets for drugs that improve cholesterol efflux and reduce heart disease risk.
- What could go wrong
- This is an observational study with only 86 participants, so findings may not apply broadly. It identifies potential targets but does not test any treatment.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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UT Southwestern Medical Center
Dallas, Texas, 75390, United States
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