Chloride pills tested for heart failure fluid control
NCT ID NCT03440970
First seen Jun 26, 2026 · Last updated Jun 26, 2026
Summary
This early-phase study tested whether giving chloride supplements (lysine chloride) to people with stable heart failure could affect their body's fluid balance. Twenty participants took either the supplement or a placebo three times daily for five days. The goal was to understand how chloride affects blood volume and kidney function, not to treat symptoms directly.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Lysine Chloride
- What this could lead to
- If successful, this could point toward a new way to manage fluid balance in heart failure patients.
- What could go wrong
- This is a very small, early-phase study with only 20 participants. It is designed to gather basic information, not to prove a treatment works.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Yale University
New Haven, Connecticut, 06510, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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- New pill could help severe heart failure patients avoid hospital