New bypass device could spare rectal cancer patients from stoma surgery

NCT ID NCT04184973

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This trial tests a temporary bypass device called CG-100 in 250 rectal cancer patients undergoing surgery. The device is placed inside the bowel to protect the surgical connection, potentially reducing the need for a temporary stoma. Researchers will compare stoma rates and complications between patients who get the device and those who receive standard stoma surgery.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

CG-100 intraluminal bypass device

What this could lead to

If it works, this device could help many rectal cancer patients avoid a temporary stoma and its associated complications after surgery.

What could go wrong

This is a mid-stage trial with 250 participants, so results may not apply to all patients. The device may not reduce stoma rates as hoped, and there are risks of device-related complications.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

rectal cancer rectal neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Email: •••••@•••••

Locations

  • Carmel Medical Center

    RECRUITING

    Haifa, 8250490, Israel

    Contact Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Colorado University Anschutz Medical Campus

    RECRUITING

    Aurora, Colorado, 80045, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact

    Contact

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • East Bank Hospital - M Health Fairview University of Minnesota Medical Center

    ACTIVE_NOT_RECRUITING

    Minneapolis, Minnesota, 55455, United States

  • Henry Ford Health System

    ACTIVE_NOT_RECRUITING

    Detroit, Michigan, 48202, United States

  • Humanitas Research Hospital

    RECRUITING

    Milan, Lombardy, 20089, Italy

    Contact Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Jefferson University Hospital

    ACTIVE_NOT_RECRUITING

    Philadelphia, Pennsylvania, 19107, United States

  • Kaiser Permanente San Diego medical Center

    RECRUITING

    San Diego, California, 92123, United States

    Contact

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Lifespan & Brown Surgical Associates

    ACTIVE_NOT_RECRUITING

    Providence, Rhode Island, 02906, United States

  • New York-Presbyterian / Weill Cornell Medical Center

    ACTIVE_NOT_RECRUITING

    New York, New York, 10021, United States

  • Rabin Medical Center

    WITHDRAWN

    Petah Tikva, 49100, Israel

  • Soroka University Medical Center

    RECRUITING

    Beersheba, 85025, Israel

    Contact Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • University of California Irvine

    RECRUITING

    Orange, California, 92868, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • University of Louisville

    ACTIVE_NOT_RECRUITING

    Louisville, Kentucky, 40202, United States

  • University of Utah Health

    ACTIVE_NOT_RECRUITING

    Salt Lake City, Utah, 84132, United States