New bypass device could spare rectal cancer patients from stoma surgery

NCT ID NCT04184973

Recruiting now Disease control Sponsor: Colospan Ltd. Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jul 07, 2026 · Updated 3 times

Summary

This trial tests a temporary bypass device called CG-100 in 250 rectal cancer patients undergoing surgery. The device is placed inside the bowel to protect the surgical connection, potentially reducing the need for a temporary stoma. Researchers will compare stoma rates and complications between patients who get the device and those who receive standard stoma surgery.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: CG-100 intraluminal bypass device
What this could lead to: If it works, this device could help many rectal cancer patients avoid a temporary stoma and its associated complications after surgery.
What could go wrong: This is a mid-stage trial with 250 participants, so results may not apply to all patients. The device may not reduce stoma rates as hoped, and there are risks of device-related complications.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for RECTAL CANCER are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

rectal cancer rectal neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

RECTAL CANCER RECTAL TUMOR RECTAL/ANAL

Contacts and locations

Locations

Asklepios
RECRUITING

Hamburg, Germany
CHUV
RECRUITING

Lausanne, Switzerland
Colorado University Anschutz Medical Campus
RECRUITING

Aurora, Colorado, 80045, United States
Henry Ford Health System
RECRUITING

Detroit, Michigan, 48202, United States
Humanitas Research Hospital
RECRUITING

Milan, Lombardy, 20089, Italy
Kaiser Permanente San Diego medical Center
RECRUITING

San Diego, California, 92123, United States
Lifespan & Brown Surgical Associates
ACTIVE_NOT_RECRUITING

Providence, Rhode Island, 02906, United States
Soroka University Medical Center
RECRUITING

Beersheba, 85025, Israel
University of California Irvine
ACTIVE_NOT_RECRUITING

Irvine, California, 92868, United States
University of Utah Health
ACTIVE_NOT_RECRUITING

Salt Lake City, Utah, 84132, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.