New plavix rival enters human testing

NCT ID NCT07619885

First seen Jun 25, 2026 · Last updated Jun 30, 2026 · Updated 3 times

Summary

This early-stage trial compares a new investigational drug, CG-0255, to the established blood thinner Plavix in 136 healthy adults aged 18-55. The goal is to see if CG-0255 is processed by the body similarly to Plavix and has the same effect on preventing blood clots. Participants will receive either CG-0255 or Plavix, and researchers will measure drug levels and platelet function.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
CG-0255 (a prodrug similar to clopidogrel/Plavix)
What this could lead to
If successful, this could lead to a new option for preventing dangerous blood clots in people with heart disease or stroke risk.
What could go wrong
This is a very early Phase 1 study in healthy volunteers, not patients. It only measures drug levels and platelet activity, not actual clinical outcomes like heart attacks. Many drugs fail in later stages.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Syneos Health

    RECRUITING

    Miami, Florida, 33101, United States

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