Blood test may spare kids with leukemia from painful bone marrow needles

NCT ID NCT07483476

Not yet recruiting Knowledge-focused Sponsor: Assistance Publique - Hôpitaux de Paris Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at whether a simple blood test can track how well treatment is working in children with acute lymphoblastic leukemia (ALL). Currently, doctors must take bone marrow samples to check for leftover cancer cells, which is invasive and painful. The researchers will compare DNA from blood samples with DNA from bone marrow to see if the blood test is just as accurate. If it works, it could mean fewer bone marrow biopsies for children undergoing leukemia treatment.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this could lead to a less invasive way to monitor leukemia in children, using a simple blood test instead of repeated bone marrow biopsies.
What could go wrong: This is an early observational study, not a treatment trial. It may find that blood tests are not accurate enough to replace bone marrow biopsies, or that results vary too much between patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

acute lymphoblastic leukemia Neoplasm, Residual Precursor Cell Lymphoblastic Leukemia-Lymphoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ACUTE LYMPHOBLASTIC LEUKEMIA (ALL)

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