New heat treatment and AI could revolutionize cervical cancer prevention

NCT ID NCT07461818

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study in El Salvador tests a new thermal ablation device (IRIS™) to treat cervical precancer and an AI algorithm to help decide who needs treatment. About 5,000 HPV-positive women aged 30-49 will receive the treatment and be followed for one year to see if the precancer is cured. The goal is to make screening and treatment faster and more effective.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

IRIS™ Thermal Ablation Device

What this could lead to

If successful, this could provide a more effective and efficient way to treat cervical precancer and triage HPV-positive women, potentially reducing cervical cancer rates.

What could go wrong

This is a single-country study with no control group, so results may not apply elsewhere. The AI triage algorithm is still being tested and may not be accurate enough for widespread use.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

cervical intraepithelial neoplasia cervical intraepithelial neoplasia grade 2/3 dysplasia of cervix human papilloma virus infection Uterine Cervical Neoplasms

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Basic Health International

    RECRUITING

    San Salvador, San Salvador Department, El Salvador

    Contact Phone: •••-•••-•••• Email: •••••@•••••