Which anesthesia keeps the brain safer during heart surgery? new study aims to find out
NCT ID NCT07248202
First seen Jun 25, 2026 · Last updated Aug 07, 2026 · Updated 2 times
Summary
This study compares two drug combinations (ketamine-lidocaine vs ketamine-fentanyl) used to put patients to sleep before heart bypass surgery. The goal is to see which combination better maintains blood flow to the brain during the procedure. The study includes 40 adults with coronary artery disease and weak heart pumping function who are scheduled for elective bypass surgery.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- ketamine, lidocaine, fentanyl
- What this could lead to
- If this trial succeeds, it could help doctors choose the best anesthesia combination to protect brain function during heart bypass surgery.
- What could go wrong
- This is a small, early-stage study with only 40 participants, so results may not apply to all patients. The study focuses on a short-term measure (brain oxygenation) rather than long-term outcomes.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Kasr Alainy Hospital
Cairo, 11562, Egypt
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Other studies related to the condition(s) this trial covers.
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