Brain stimulation study probes Cerebellum's role in dystonia

NCT ID NCT01272154

Completed Knowledge-focused Sponsor: Institut National de la Santé Et de la Recherche Médicale, France Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study investigates how the cerebellum influences brain plasticity in people with dystonia, a movement disorder, and in healthy volunteers. Researchers use non-invasive brain stimulation (TMS) to temporarily change cerebellar activity and measure its effects on brain plasticity and dystonia symptoms. The goal is to better understand the cerebellum's role in the condition, which could inform future treatments.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: transcranial magnetic stimulation
What this could lead to: If successful, this could clarify the role of the cerebellum in dystonia and point toward new brain-stimulation treatments.
What could go wrong: This is a small, early-stage study focused on understanding brain mechanisms, not testing a treatment. Results may not lead to direct therapies.

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Conditions

The condition(s) this trial relates to.

acquired torsion dystonia cerebral palsy Dystonia dystonic disorder focal dystonia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

DYSTONIA

Contacts and locations

Locations

Hpôpital Pitié Sapétrière - U 975 Plate forme " Pole Exploration de l'homme : Gait, Equilibrium, Posture, and Movement "

Paris, 75013, France

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