Can immune cell therapy stop type 1 diabetes before it starts?

NCT ID NCT06688331

First seen Jan 16, 2026 · Last updated May 13, 2026 · Updated 15 times

Summary

This study tests whether a combination of special immune cells (Tregs) and an antibody drug (rituximab) can delay or prevent type 1 diabetes in children aged 6-16 who are at high risk but still produce insulin normally. About 150 participants will be randomly assigned to one of four groups, including placebo, and followed for up to five years. The goal is to see if the treatment can keep blood sugar levels normal longer and is safe for children.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Centrum Medyczne Medyk Sp. z o.o. S.K.

    RECRUITING

    Rzeszów, 35-326, Poland

    Contact

  • Gornoslaskie Centrum Zdrowia Dziecka Im. Sw. Jana Pawla II Samodzielny Publiczny Szpital Kliniczny Nr 6 Slaskiego Uniwersytetu Medycznego W Katowicach

    NOT_YET_RECRUITING

    Katowice, 40-752, Poland

    Contact

  • Uniwersytecki Dzieciecy Szpital Kliniczny Im. L. Zamenhofa W Bialymstoku

    RECRUITING

    Bialystok, 15-269, Poland

    Contact

  • Uniwersytecki Szpital Dzieciecy w Lublinie

    RECRUITING

    Lublin, 20-093, Poland

    Contact

  • Uniwersytecki Szpital Kliniczny Im. Jana Mikulicza-Radeckiego We Wroclawiu

    RECRUITING

    Wroclaw, 50-556, Poland

    Contact

  • Uniwersytecki Szpital Kliniczny w Opolu

    RECRUITING

    Opole, 45-401, Poland

    Contact

  • Uniwersyteckie Centrum Kliniczne

    RECRUITING

    Gdansk, 80-211, Poland

    Contact

  • Uniwersytet Medyczny W Lodzi

    RECRUITING

    Lodz, 90-419, Poland

    Contact

Conditions

Explore the condition pages connected to this study.