Smart dosing of antibiotics may cut infection risk after colon surgery

NCT ID NCT05253339

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This study tested whether giving the antibiotic cefoxitin using a target-controlled infusion pump works better than the standard method to prevent surgical site infections in patients having colon or rectal surgery. About 2,500 adults took part. The goal was to see if the new method lowers infection rates.

What this could mean

Our plain-language read of the trial. This is informational only โ€” not medical advice or a prediction.

Active substance
cefoxitin
What this could lead to
If successful, this could show that target-controlled infusion reduces surgical site infections better than the standard method.
What could go wrong
This is a completed single-center trial; results may not apply to other hospitals or surgeries. The benefit over standard dosing may be small or absent.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Asan Medical Center

    Seoul, Songpa-Gu,, 05505, South Korea

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