New drug combo targets tumor blood supply and growth

NCT ID NCT01364051

First seen Nov 01, 2025 · Last updated Jun 11, 2026 · Updated 40 times

Summary

This early-phase study tested two experimental drugs, cediranib and selumetinib, in 19 people with advanced solid tumors that had stopped responding to standard treatments. The goal was to find the safest dose and check for side effects. The drugs work by blocking blood vessel growth and key enzymes that cancer cells need to grow.

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Contacts and locations

Locations

  • Mayo Clinic in Florida

    Jacksonville, Florida, 32224-9980, United States

  • Mayo Clinic in Rochester

    Rochester, Minnesota, 55905, United States

Conditions

Explore the condition pages connected to this study.