Engineered immune cells aim to tame chronic GVHD in first human trial
NCT ID NCT05993611
First seen Nov 11, 2025 · Last updated May 16, 2026 · Updated 25 times
Summary
This early-stage trial tests a new treatment called CD6-CAR Tregs for people with chronic graft-versus-host disease (cGVHD), a complication after a stem cell transplant. The therapy uses specially modified immune cells to calm the overactive immune response that causes cGVHD. The study will enroll 27 participants to check safety, side effects, and the best dose. It is currently suspended.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Locations
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City of Hope Medical Center
Duarte, California, 91010, United States
Conditions
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